Saturday, September 24, 2011

Children born after the unplanned pregnancy is slower to develop

Children born after the unplanned pregnancies tend to have a more limited vocabulary and poorer non-verbal and spatial abilities. However, this almost entirely explained by disadvantaged conditions, according to a new study published today in the British Medical Journal. In the same study reported no adverse effects of infertility treatment for children.
In the United Kingdom, 30-40% of pregnancies ending in childbirth is unplanned, while the number of children born after assisted reproductive technologies is growing every year.
It is already known that children born after prolonged time capture or assisted reproduction are at greater risk of poor health outcomes such as premature birth, low birth weight, congenital anomalies, and some researchers have reported lower cognitive (mental) scores in these children.
Unplanned pregnancies are also poorer results, but there was little investigation to assess whether a child development associated with pregnancy planning.
A team of researchers in the United Kingdom set out to explore how pregnancy planning, time perception and treatment of infertility, the influence of child cognitive development in three to five years.
They analyzed data from approximately 12,000 children from Millennium study, a major study of Uk families and infants born in 2000-2. Were interviews with parents who took part when their child was aged between nine months and then be reconsidered when the child was three to five years.
Mothers reported whether the pregnancy was planned, their emotions at first pregnant, to arrest and details of any processing of sterility.
Each child is verbal, non verbal and spatial abilities were tested at the age of three and five British ability scales.
Initial analysis showed that children born after an unplanned pregnancy was four to five months behind the planned children to verbal abilities, whereas children born after assisted reproduction was three to four months.
However, these differences all but disappeared when the researchers took into account the socio-economic conditions of each child.
The authors conclude: "these differences are almost entirely explained by socio-economic factors, providing further evidence for the influence of socioeconomic inequalities in the lives of children in the United Kingdom. To help children achieve their full potential, policy-makers continue to target social inequalities. "

Provided by the British Medical Journal (news: web)

health and safety

Children born after the unplanned pregnancy is slower to develop

Children born after the unplanned pregnancies tend to have a more limited vocabulary and poorer non-verbal and spatial abilities. However, this almost entirely explained by disadvantaged conditions, according to a new study published today in the British Medical Journal. In the same study reported no adverse effects of infertility treatment for children.
In the United Kingdom, 30-40% of pregnancies ending in childbirth is unplanned, while the number of children born after assisted reproductive technologies is growing every year.
It is already known that children born after prolonged time capture or assisted reproduction are at greater risk of poor health outcomes such as premature birth, low birth weight, congenital anomalies, and some researchers have reported lower cognitive (mental) scores in these children.
Unplanned pregnancies are also poorer results, but there was little investigation to assess whether a child development associated with pregnancy planning.
A team of researchers in the United Kingdom set out to explore how pregnancy planning, time perception and treatment of infertility, the influence of child cognitive development in three to five years.
They analyzed data from approximately 12,000 children from Millennium study, a major study of Uk families and infants born in 2000-2. Were interviews with parents who took part when their child was aged between nine months and then be reconsidered when the child was three to five years.
Mothers reported whether the pregnancy was planned, their emotions at first pregnant, to arrest and details of any processing of sterility.
Each child is verbal, non verbal and spatial abilities were tested at the age of three and five British ability scales.
Initial analysis showed that children born after an unplanned pregnancy was four to five months behind the planned children to verbal abilities, whereas children born after assisted reproduction was three to four months.
However, these differences all but disappeared when the researchers took into account the socio-economic conditions of each child.
The authors conclude: "these differences are almost entirely explained by socio-economic factors, providing further evidence for the influence of socioeconomic inequalities in the lives of children in the United Kingdom. To help children achieve their full potential, policy-makers continue to target social inequalities. "

Provided by the British Medical Journal (news: web)

health and safety

Tuesday, September 20, 2011

Mexican papayas sicken 99 in the u.s.

Mexican papayas are tainted with salmonella sickened 99 people in the United States, the Centers for disease control and prevention said Tuesday.
No mention of any deaths, but the outbreak spans 23 States and health authorities warned people not to eat fresh, whole papayas imported from Mexico by Agromed production of Alice, Texas.
"Consumers should not eat recalled papayas, and restaurant and food service operators must not serve them," the CDC said.
The company issued a voluntary recall Friday of all Blondie, Yaya, Mananita and Tastylicious chip papayas, which sold prior to July 23 because they could be contaminated.
The first cases in the outbreak of salmonella agona in January and has continued to be reported through mid-July, the CDC said. Twenty-five of the 99 diseases in Texas, the worst hit MAS.
In Mexico, the Ministry of agriculture said Tuesday that it is too early to know whether the Mexican papayas was the source of the disease.
US and Mexican authorities "engage in research in both countries to determine the source of the outbreak of salmonella" that it is time for any conclusive comment on the cause, said Enrique Sanchez, who heads up Mexican food safety.
"For now, Mexican papayas cannot be named as the source of the disease," Sanchez said.
Salmonella poisoning usually causes diarrhea, fever and stomach within 12 to 72 hours of eating and symptoms may take up to one week.
Most people recover without treatment, but it could be people with weak immune system, the elderly and very young people at risk, if the infection spreads to the bloodstream.

(c) AFP 2011


health and safety

Mexican papayas sicken 99 in the u.s.

Mexican papayas are tainted with salmonella sickened 99 people in the United States, the Centers for disease control and prevention said Tuesday.
No mention of any deaths, but the outbreak spans 23 States and health authorities warned people not to eat fresh, whole papayas imported from Mexico by Agromed production of Alice, Texas.
"Consumers should not eat recalled papayas, and restaurant and food service operators must not serve them," the CDC said.
The company issued a voluntary recall Friday of all Blondie, Yaya, Mananita and Tastylicious chip papayas, which sold prior to July 23 because they could be contaminated.
The first cases in the outbreak of salmonella agona in January and has continued to be reported through mid-July, the CDC said. Twenty-five of the 99 diseases in Texas, the worst hit MAS.
In Mexico, the Ministry of agriculture said Tuesday that it is too early to know whether the Mexican papayas was the source of the disease.
US and Mexican authorities "engage in research in both countries to determine the source of the outbreak of salmonella" that it is time for any conclusive comment on the cause, said Enrique Sanchez, who heads up Mexican food safety.
"For now, Mexican papayas cannot be named as the source of the disease," Sanchez said.
Salmonella poisoning usually causes diarrhea, fever and stomach within 12 to 72 hours of eating and symptoms may take up to one week.
Most people recover without treatment, but it could be people with weak immune system, the elderly and very young people at risk, if the infection spreads to the bloodstream.

(c) AFP 2011


health and safety

Saturday, September 17, 2011

I think healthy to eat healthy: scientists demonstrate link between attention and self-regulation

خطأ hides selsla elghaa vi alnos alasasi lersala elarid llamlia ' Translate '. tom tegaus (8192) elhasa alnsbia lltol lmhatoa alslsla athnaa قراءة alaksa bayanat XML. weimkn zeyada elhasa alnsbia wezelk btghier hazaa alkhasia kaen almstkhedm alla MaxStringContentLength XmlDictionaryReaderQuotas enad enshaa XML قارئ. alistar 1 ' almoodie 2331.Think Healthy, Eat Healthy: Caltech Scientists Show Link Between Attention, Self-Control
Enlarge
When the dorsolateral prefrontal cortex (dlPFC) is active, it allows the ventral medial prefrontal cortex (vmPFC) to take into account health benefits as well as taste when it assigns a value to a particular food. [Credit: Caltech/Hare, et. al.](Medical Xpress)--you're trying to decide what to eat for dinner. Should it be the chicken and broccoli? The super-sized fast-food burger? Skip it entirely and just get someRocky Road?
Making that choice, it turns out, is a complex neurological exercise. But, according to researchers from the California Institute of Technology (Caltech), it's one that can be influenced by a simple shifting of attention toward the healthy side of life. And that shift may provide strategies to help us all make choices — takes on not just in terms of the foods we eat, but in other areas, like whether or not we actually pick up a.
Their research is described in a paper published in the July 27 issue of the Journal of Neuroscience.
When you decide what to eat, not only does your brain need to figure out how it feels about a food's taste versus its health benefits versus its size or even its packaging, but it needs to decide the importance of each of those attributes relative to the others. And it needs to do all of this more-or-less instantaneously.
When the dorsolateral prefrontal cortex (dlPFC) is active, it allows the ventral medial prefrontal cortex (vmPFC) to take into account health benefits as well as taste when it assigns a value to a particular food.
[Credit: Caltech/Hare, et. al.]
Antonio Rangel, professor of economics and neuroscience at Caltech, has been studying this value-deriving and decision-making process for years now. Along with Todd Hare — a former postdoc at Caltech who is now an assistant professor of neuroeconomics at the University of Zurich in Switzerland — he published a paper in Science in 2009 describing differences in the brains of people who are better at exercising self-control than others. What they found was that while everyone uses the same area of the brain — the ventral medial prefrontal cortex, or vmPFC — to make value-laden decisions like what to munch on, there's a second brain area — the dorsolateral prefrontal cortex, or dlPFC — that seems to come to life when a person is using self-control during the decision-making process.
In other words, when the dlPFC is active, it allows the vmPFC to take into account health benefits as well as taste when it assigns a value to a particular food.

The new study goes a step further, showing that there seem to be ways to help kickstart the dlPFC through the use of what Hare calls "external pool cues" that allow us to exhibit more self-control than we might have otherwise.
The researchers came to their conclusions based on data from a brain-imaging experiment conducted with 33 adult volunteers, none of whom were following a specific diet or trying to lose weight for any reason. Each of the volunteers was shown 180 different food items — from chips and candy bars to intros and broccoli — through a set of video goggles while in a functional magnetic resonance imaging (fMRI) machine.
The hungry subjects — they were asked to fast for at least three hours prior to the experiment — were given up to three seconds to respond to each picture with a decision about whether or not they'd want to eat the food shown after the experiment was over. They could either give the food a strong "no, no" a "," a "yes" or a "strong yes." Once all of the images had been flipped through, a single food image was chosen at random? if the volunteer had said "yes" or "strong yes" to the idea of eating that food, he or she was served that item.
"Because only one random trial was selected to count ', '" says Rangel, "the optimal strategy for subjects is to treat each decision as if it were the only one."
Simple, right? But here's the catch: before every 10 food choices, an instruction would come on the screen for five seconds telling the subjects either to "consider the healthiness," "consider the tastiness," or "make decisions naturally." This meant that of the 180 decisions, the subjects made 60 in each of the three "instruction conditions."
What this was meant to do, Rangel explains, is shift the subject's attention during the experiment and, potentially, shift the way in which they made decisions.
Afterward — outside the scanner — the subjects were asked to rate the same foods on both a tastiness scale (very untasty, untasty, tasty, very tasty) and a scale healthiness (very unhealthy, very unhealthy, healthy, healthy). That way, the researchers were able to associate the choices the subjects made during the brain scan with their stated perceptions of those foods ' attributes — showing that a subject who chose broccoli during the "consider the healthiness" portion of the test might think of it as untasty nonetheless.
The researchers then classified the foods for each subject based on that subject's ratings: unhealthy-untasty, healthy-untasty, unhealthy-tasty, and healthy-tasty. Unsurprisingly, people chose healthy-tasty foods no matter where their attention had been directed.
Things got interesting when the researchers looked at the other three categories, however. Among their findings:
When thinking about healthiness, subjects were less likely to eat unhealthy foods, whether or not they deemed them to be tasty, and more likely to eat healthy-untasty foods.
Being asked to think about healthiness led subjects to say "no" to foods more often than they did when asked to make decisions naturally.
There were no real differences between the choices made during the "consider the tastiness" and "make decisions naturally the western portion of the Medley".When the researchers turned to the fMRI results, they found that the vmPFC was, as influenza, "more responsive to the healthiness of food in the presence of health pool cues," says Rangel. And they'd, as seen previously, the robustness of that response was due to the latest of the dlPFC — that bastion hotel of self-control — which was much quieter when the study's subjects were thinking about taste or their own personal choice than when they were asked to healthiness throw into the equation.
"This latest of the increased health signals on the vmPFC results in an overall value for the food that is based more on its health properties than is the case when the subject's attention is not" focused on healthiness, "says Hare.
These results are most likely not limited just to choices about food, says Hare. "Our findings are also relevant to the current warnings actually changes to many governments have started to make," he notes. "These changes include adding graphical images of the health risks of smoking. It for improvement with regard to be seen whether these images will be more effective in drawing attention to the unhealthiness of smoking than the text warnings. If the graphical warnings do increase attention to health, then our results suggest that they could decrease the desire to smoke. "
Jonathan Malmaud, a former research assistant at Caltech who is now a graduate student at MIT, was also an author on the Journal of Neuroscience paper, Focusing attention on the health aspects of foods changes value signals in the vmPFC and improves dietary choice. " The scientists ' work was funded by a grant from the National Science Foundation.

Provided by California Institute of Technology (news: web)

health and safety

I think healthy to eat healthy: scientists demonstrate link between attention and self-regulation

خطأ hides selsla elghaa vi alnos alasasi lersala elarid llamlia ' Translate '. tom tegaus (8192) elhasa alnsbia lltol lmhatoa alslsla athnaa قراءة alaksa bayanat XML. weimkn zeyada elhasa alnsbia wezelk btghier hazaa alkhasia kaen almstkhedm alla MaxStringContentLength XmlDictionaryReaderQuotas enad enshaa XML قارئ. alistar 1 ' almoodie 2331.Think Healthy, Eat Healthy: Caltech Scientists Show Link Between Attention, Self-Control
Enlarge
When the dorsolateral prefrontal cortex (dlPFC) is active, it allows the ventral medial prefrontal cortex (vmPFC) to take into account health benefits as well as taste when it assigns a value to a particular food. [Credit: Caltech/Hare, et. al.](Medical Xpress)--you're trying to decide what to eat for dinner. Should it be the chicken and broccoli? The super-sized fast-food burger? Skip it entirely and just get someRocky Road?
Making that choice, it turns out, is a complex neurological exercise. But, according to researchers from the California Institute of Technology (Caltech), it's one that can be influenced by a simple shifting of attention toward the healthy side of life. And that shift may provide strategies to help us all make choices — takes on not just in terms of the foods we eat, but in other areas, like whether or not we actually pick up a.
Their research is described in a paper published in the July 27 issue of the Journal of Neuroscience.
When you decide what to eat, not only does your brain need to figure out how it feels about a food's taste versus its health benefits versus its size or even its packaging, but it needs to decide the importance of each of those attributes relative to the others. And it needs to do all of this more-or-less instantaneously.
When the dorsolateral prefrontal cortex (dlPFC) is active, it allows the ventral medial prefrontal cortex (vmPFC) to take into account health benefits as well as taste when it assigns a value to a particular food.
[Credit: Caltech/Hare, et. al.]
Antonio Rangel, professor of economics and neuroscience at Caltech, has been studying this value-deriving and decision-making process for years now. Along with Todd Hare — a former postdoc at Caltech who is now an assistant professor of neuroeconomics at the University of Zurich in Switzerland — he published a paper in Science in 2009 describing differences in the brains of people who are better at exercising self-control than others. What they found was that while everyone uses the same area of the brain — the ventral medial prefrontal cortex, or vmPFC — to make value-laden decisions like what to munch on, there's a second brain area — the dorsolateral prefrontal cortex, or dlPFC — that seems to come to life when a person is using self-control during the decision-making process.
In other words, when the dlPFC is active, it allows the vmPFC to take into account health benefits as well as taste when it assigns a value to a particular food.

The new study goes a step further, showing that there seem to be ways to help kickstart the dlPFC through the use of what Hare calls "external pool cues" that allow us to exhibit more self-control than we might have otherwise.
The researchers came to their conclusions based on data from a brain-imaging experiment conducted with 33 adult volunteers, none of whom were following a specific diet or trying to lose weight for any reason. Each of the volunteers was shown 180 different food items — from chips and candy bars to intros and broccoli — through a set of video goggles while in a functional magnetic resonance imaging (fMRI) machine.
The hungry subjects — they were asked to fast for at least three hours prior to the experiment — were given up to three seconds to respond to each picture with a decision about whether or not they'd want to eat the food shown after the experiment was over. They could either give the food a strong "no, no" a "," a "yes" or a "strong yes." Once all of the images had been flipped through, a single food image was chosen at random? if the volunteer had said "yes" or "strong yes" to the idea of eating that food, he or she was served that item.
"Because only one random trial was selected to count ', '" says Rangel, "the optimal strategy for subjects is to treat each decision as if it were the only one."
Simple, right? But here's the catch: before every 10 food choices, an instruction would come on the screen for five seconds telling the subjects either to "consider the healthiness," "consider the tastiness," or "make decisions naturally." This meant that of the 180 decisions, the subjects made 60 in each of the three "instruction conditions."
What this was meant to do, Rangel explains, is shift the subject's attention during the experiment and, potentially, shift the way in which they made decisions.
Afterward — outside the scanner — the subjects were asked to rate the same foods on both a tastiness scale (very untasty, untasty, tasty, very tasty) and a scale healthiness (very unhealthy, very unhealthy, healthy, healthy). That way, the researchers were able to associate the choices the subjects made during the brain scan with their stated perceptions of those foods ' attributes — showing that a subject who chose broccoli during the "consider the healthiness" portion of the test might think of it as untasty nonetheless.
The researchers then classified the foods for each subject based on that subject's ratings: unhealthy-untasty, healthy-untasty, unhealthy-tasty, and healthy-tasty. Unsurprisingly, people chose healthy-tasty foods no matter where their attention had been directed.
Things got interesting when the researchers looked at the other three categories, however. Among their findings:
When thinking about healthiness, subjects were less likely to eat unhealthy foods, whether or not they deemed them to be tasty, and more likely to eat healthy-untasty foods.
Being asked to think about healthiness led subjects to say "no" to foods more often than they did when asked to make decisions naturally.
There were no real differences between the choices made during the "consider the tastiness" and "make decisions naturally the western portion of the Medley".When the researchers turned to the fMRI results, they found that the vmPFC was, as influenza, "more responsive to the healthiness of food in the presence of health pool cues," says Rangel. And they'd, as seen previously, the robustness of that response was due to the latest of the dlPFC — that bastion hotel of self-control — which was much quieter when the study's subjects were thinking about taste or their own personal choice than when they were asked to healthiness throw into the equation.
"This latest of the increased health signals on the vmPFC results in an overall value for the food that is based more on its health properties than is the case when the subject's attention is not" focused on healthiness, "says Hare.
These results are most likely not limited just to choices about food, says Hare. "Our findings are also relevant to the current warnings actually changes to many governments have started to make," he notes. "These changes include adding graphical images of the health risks of smoking. It for improvement with regard to be seen whether these images will be more effective in drawing attention to the unhealthiness of smoking than the text warnings. If the graphical warnings do increase attention to health, then our results suggest that they could decrease the desire to smoke. "
Jonathan Malmaud, a former research assistant at Caltech who is now a graduate student at MIT, was also an author on the Journal of Neuroscience paper, Focusing attention on the health aspects of foods changes value signals in the vmPFC and improves dietary choice. " The scientists ' work was funded by a grant from the National Science Foundation.

Provided by California Institute of Technology (news: web)

health and safety

Monday, September 12, 2011

Offset by private health insurance for children of families: study

Families rely increasingly on public health insurance plans provide coverage for their children, a growing trend researchers associated with job losses, coverage changes to private insurance health plans, and expanded access to public plans, according to new research by the Carsey Institute at the University of New Hampshire.
The trend is particularly strong in rural and urban areas, which traditionally had lower rates of coverage from suburban areas.
"When people are unemployed, not only losing their private insurance based on employment but, with the loss of income, families may be eligible for public projects recently. In addition, as a rule the poor economy and expanded eligibility for public projects may also play a more direct roles in changing health insurance rates among children, "the researchers reported.
Health insurance for children is provided mainly through Medicaid and children's health insurance program (SCHIP) of. Court taking into account a wide range of significant funding cuts for both programs as part of negotiations over the budget deficit, with suggestions ranging from cutting $ 100 billion over ten years to 1 trillion dollars over the same period.
The main findings of this survey show:
Health insurance coverage among children increased 1.3 percentage points from 2008-2009 in the United States, with the largest growth in central cities and rural areas.
The Northeast still has the highest percentage of coverage, with more than 95 percent of children covered. In the South has the lowest coverage rates, 89 percent.
Forty-four States, plus Washington DC and Puerto Rico had been a significant increase in the number of children covered by health insurance.
Twenty-seven Member States saw a decline in private health insurance coverage for children.
Children in the Central cities of the Midwest experienced the largest shift from private to public insurers in 2009. private insurance coverage decreased 4.3 percentage points, while the public coverage increased by 6,5%, approximately 9% of children at the national level are not covered by any form of insurance. More than half of these children are eligible for coverage through Medicaid or SCHIP.
"Research shows that most of these eligible children coming from Member States with low participation rates and are disproportionately within the query. Because those who have health insurance are healthier overall and, more importantly, because healthy children are more likely to become healthy adults, focusing on the coverage of eligible children should remain at the forefront of the agenda of the nation, "the researchers reported.

More info: the full report of this investigation, "All children covered by health insurance has increased in 2009, is available at http://www.carseyi … h. php? id = 168

Provided by the University of New Hampshire (news: web)

health and safety

Offset by private health insurance for children of families: study

Families rely increasingly on public health insurance plans provide coverage for their children, a growing trend researchers associated with job losses, coverage changes to private insurance health plans, and expanded access to public plans, according to new research by the Carsey Institute at the University of New Hampshire.
The trend is particularly strong in rural and urban areas, which traditionally had lower rates of coverage from suburban areas.
"When people are unemployed, not only losing their private insurance based on employment but, with the loss of income, families may be eligible for public projects recently. In addition, as a rule the poor economy and expanded eligibility for public projects may also play a more direct roles in changing health insurance rates among children, "the researchers reported.
Health insurance for children is provided mainly through Medicaid and children's health insurance program (SCHIP) of. Court taking into account a wide range of significant funding cuts for both programs as part of negotiations over the budget deficit, with suggestions ranging from cutting $ 100 billion over ten years to 1 trillion dollars over the same period.
The main findings of this survey show:
Health insurance coverage among children increased 1.3 percentage points from 2008-2009 in the United States, with the largest growth in central cities and rural areas.
The Northeast still has the highest percentage of coverage, with more than 95 percent of children covered. In the South has the lowest coverage rates, 89 percent.
Forty-four States, plus Washington DC and Puerto Rico had been a significant increase in the number of children covered by health insurance.
Twenty-seven Member States saw a decline in private health insurance coverage for children.
Children in the Central cities of the Midwest experienced the largest shift from private to public insurers in 2009. private insurance coverage decreased 4.3 percentage points, while the public coverage increased by 6,5%, approximately 9% of children at the national level are not covered by any form of insurance. More than half of these children are eligible for coverage through Medicaid or SCHIP.
"Research shows that most of these eligible children coming from Member States with low participation rates and are disproportionately within the query. Because those who have health insurance are healthier overall and, more importantly, because healthy children are more likely to become healthy adults, focusing on the coverage of eligible children should remain at the forefront of the agenda of the nation, "the researchers reported.

More info: the full report of this investigation, "All children covered by health insurance has increased in 2009, is available at http://www.carseyi … h. php? id = 168

Provided by the University of New Hampshire (news: web)

health and safety

Thursday, September 8, 2011

Vitamin d relieves joint, muscle pain for patients with breast cancer

Vitamin D relieves joint, muscle pain for breast cancer patients

Zoom

High-dose vitamin d relieves pain for many patients of breast cancer with estrogen-lowering drugs, a new study shows. Credit: Michael c. Purdyhigh-dose vitamin d relieves pain for many breast cancer patients estrogen-lowering drugs, according to a new study from Washington University School of medicine in St. Louis.

Drugs, known as aromatase inhibitors, commonly referred to shrink breast tumors that are powered by the hormone estrogen and help prevent recurrence of cancer. It is less toxic than chemotherapy, but for many patients, the drug can cause serious musculoskeletal discomfort, including pain and stiffness in the hands, wrists, knees, hips, lower back, shoulders and legs.

"Approximately half of patients may experience these symptoms," says Antonella Rastelli l., MD, Assistant Professor of medicine and first author of the study, published online in the Journal for research on breast cancer and treatment. "We do not know exactly why pain occurs, but can be very debilitating — the point that patients decide to block the aromatase inhibitors."

This video is not supported by your browser at this time.Washington University physicians found that high doses of vitamin d helps to relieve pain in breast cancer patients estrogen-lowering drugs. Known as aromatase inhibitors, drugs to treat breast tumors being supplied by the hormone estrogen. It is less toxic than chemotherapy, but many patients experience severe musculoskeletal discomfort, including pain and stiffness in the hands, knees, hips, lower back, shoulders and legs. Credit: Clark BowenBecause drugs reduce recurrence of cancer, found a way to help patients remain on is important for long-term survival without relapse, according to Rastelli. Aromatase inhibitors are prescribed to post-menopausal women for at least five years and more frequently after the diagnosis of breast cancer. There is some evidence that patients have the experience of drug side effects are less likely to see the cancer returned, providing even more incentive to help these patients still.

Rastelli was by Marie e. Taylor, MD, Assistant Professor of Radiation Oncology, who first noticed that patients with aromatase inhibitors that experienced this pain found some relief from high doses of vitamin d.

Both the Group recruited Rastelli 60 patients reported pain and distress associated with anastrozole, one of the three FDA-approved aromatase inhibitors. Patients examined also had low vitamin d levels. Half of the Group were randomized to receive the recommended daily intake of vitamin d (400 IU) plus a capsule unit-50,000 vitamin d once a week. The other half received the daily intake of 400 units of vitamin d plus weekly placebo. All subjects received 1,000 milligrams of calcium daily throughout the study.

Patients in the study reported no pain suffered through three different questionnaires. They were asked to quantify the intensity of pain, as well as the report how the pain changed the climate, influenced their work and in relationships and everyday activities. The results show that patients with high-dose vitamin d each week reported significantly less musculoskeletal pain and also were less likely to experience the pain that interfered with daily life.

"High-dose vitamin d seems to be really effective at reducing musculoskeletal pain caused by aromatase inhibitors," says Rastelli. "Patients the impression weekly vitamin d better because their pain and sometimes strays completely reduced. This makes the drug much more tolerable. Millions of women worldwide to aromatase inhibitor therapy, and can we have another ' tool ' to remain in this anymore. "

Anastrozole as used in this study, two other aromatase inhibitors approved by FDA, letrozole and exemestane, should also give rise to musculoskeletal pain. Taking into account the similar reactions, Rastelli says patients about these drugs may benefit from high doses of vitamin d.

Vitamin used in this study is of a type derived from a plant called Vitamin D2. Rastelli says that achieves the best results when given weekly, because this body metabolizes within seven to 10 days. Rastelli and her colleagues used high-dose Vitamin D3, which remains in the body longer.

"This was a very carefully conducted study, and the control of the standard makes the findings very impressive," says Matthew j. Ellis, MD, Ph.d., senior author of the study and Director of the breast cancer program at the Center, Alvin j. Siteman cancer at Barnes-Jewish Hospital and Washington University School of medicine in St. Louis. "We have to take up these findings further to determine the most effective and safe approach for additional vitamin d in our patients with breast cancer."

Since vitamin d helps the body absorb calcium, too much of it can cause high levels of calcium in the urine, which may increase the risk of kidney stones. Possible reactions to stress the importance of patient monitoring urine calcium levels taking high doses of vitamin d.

"It is important to monitor patients, but overall it seems to be very safe," says Rastelli. Because Vitamin D2 is removed from the body so quickly, it is very difficult to overdose. "

In addition to the relief of pain, the Group wanted to examine whether it could protect vitamin d in the loss of bone that is often regarded as aromatase inhibitors in patients. The researchers measured each patient bone density at the beginning of the study again after six months.

Perhaps because of its role in calcium absorption, high-dose vitamin d appear to contribute to the maintenance of bone density in the neck of the femur, at the top of the thighbone near hip hinge. Although the result did not reach statistical significance, Rastelli calls the promising and worth further study.

"Great to have something simple as vitamin d to help patients to alleviate some of this pain," says Rastelli. "It is not toxic — does not cause significant side effects. And if that is actually to protect against bone loss, which is even better. "

More info: Rastelli AL, Taylor, Gao F, Armamento Villareal-R, S-Jamalabadi Majidi, Napoli n., Ellis, MJ. Vitamin d and aromatase inhibitor-induced musculoskeletal symptoms (AIMSS): a phase II, double-blind, placebo-controlled, randomized trial separated. Research on breast cancer and treatment. Online June 2011.

Provided by Washington University School of Medicine (news: web)


View the original article here

Vitamin d relieves joint, muscle pain for patients with breast cancer

Vitamin D relieves joint, muscle pain for breast cancer patients

Zoom

High-dose vitamin d relieves pain for many patients of breast cancer with estrogen-lowering drugs, a new study shows. Credit: Michael c. Purdyhigh-dose vitamin d relieves pain for many breast cancer patients estrogen-lowering drugs, according to a new study from Washington University School of medicine in St. Louis.

Drugs, known as aromatase inhibitors, commonly referred to shrink breast tumors that are powered by the hormone estrogen and help prevent recurrence of cancer. It is less toxic than chemotherapy, but for many patients, the drug can cause serious musculoskeletal discomfort, including pain and stiffness in the hands, wrists, knees, hips, lower back, shoulders and legs.

"Approximately half of patients may experience these symptoms," says Antonella Rastelli l., MD, Assistant Professor of medicine and first author of the study, published online in the Journal for research on breast cancer and treatment. "We do not know exactly why pain occurs, but can be very debilitating — the point that patients decide to block the aromatase inhibitors."

This video is not supported by your browser at this time.Washington University physicians found that high doses of vitamin d helps to relieve pain in breast cancer patients estrogen-lowering drugs. Known as aromatase inhibitors, drugs to treat breast tumors being supplied by the hormone estrogen. It is less toxic than chemotherapy, but many patients experience severe musculoskeletal discomfort, including pain and stiffness in the hands, knees, hips, lower back, shoulders and legs. Credit: Clark BowenBecause drugs reduce recurrence of cancer, found a way to help patients remain on is important for long-term survival without relapse, according to Rastelli. Aromatase inhibitors are prescribed to post-menopausal women for at least five years and more frequently after the diagnosis of breast cancer. There is some evidence that patients have the experience of drug side effects are less likely to see the cancer returned, providing even more incentive to help these patients still.

Rastelli was by Marie e. Taylor, MD, Assistant Professor of Radiation Oncology, who first noticed that patients with aromatase inhibitors that experienced this pain found some relief from high doses of vitamin d.

Both the Group recruited Rastelli 60 patients reported pain and distress associated with anastrozole, one of the three FDA-approved aromatase inhibitors. Patients examined also had low vitamin d levels. Half of the Group were randomized to receive the recommended daily intake of vitamin d (400 IU) plus a capsule unit-50,000 vitamin d once a week. The other half received the daily intake of 400 units of vitamin d plus weekly placebo. All subjects received 1,000 milligrams of calcium daily throughout the study.

Patients in the study reported no pain suffered through three different questionnaires. They were asked to quantify the intensity of pain, as well as the report how the pain changed the climate, influenced their work and in relationships and everyday activities. The results show that patients with high-dose vitamin d each week reported significantly less musculoskeletal pain and also were less likely to experience the pain that interfered with daily life.

"High-dose vitamin d seems to be really effective at reducing musculoskeletal pain caused by aromatase inhibitors," says Rastelli. "Patients the impression weekly vitamin d better because their pain and sometimes strays completely reduced. This makes the drug much more tolerable. Millions of women worldwide to aromatase inhibitor therapy, and can we have another ' tool ' to remain in this anymore. "

Anastrozole as used in this study, two other aromatase inhibitors approved by FDA, letrozole and exemestane, should also give rise to musculoskeletal pain. Taking into account the similar reactions, Rastelli says patients about these drugs may benefit from high doses of vitamin d.

Vitamin used in this study is of a type derived from a plant called Vitamin D2. Rastelli says that achieves the best results when given weekly, because this body metabolizes within seven to 10 days. Rastelli and her colleagues used high-dose Vitamin D3, which remains in the body longer.

"This was a very carefully conducted study, and the control of the standard makes the findings very impressive," says Matthew j. Ellis, MD, Ph.d., senior author of the study and Director of the breast cancer program at the Center, Alvin j. Siteman cancer at Barnes-Jewish Hospital and Washington University School of medicine in St. Louis. "We have to take up these findings further to determine the most effective and safe approach for additional vitamin d in our patients with breast cancer."

Since vitamin d helps the body absorb calcium, too much of it can cause high levels of calcium in the urine, which may increase the risk of kidney stones. Possible reactions to stress the importance of patient monitoring urine calcium levels taking high doses of vitamin d.

"It is important to monitor patients, but overall it seems to be very safe," says Rastelli. Because Vitamin D2 is removed from the body so quickly, it is very difficult to overdose. "

In addition to the relief of pain, the Group wanted to examine whether it could protect vitamin d in the loss of bone that is often regarded as aromatase inhibitors in patients. The researchers measured each patient bone density at the beginning of the study again after six months.

Perhaps because of its role in calcium absorption, high-dose vitamin d appear to contribute to the maintenance of bone density in the neck of the femur, at the top of the thighbone near hip hinge. Although the result did not reach statistical significance, Rastelli calls the promising and worth further study.

"Great to have something simple as vitamin d to help patients to alleviate some of this pain," says Rastelli. "It is not toxic — does not cause significant side effects. And if that is actually to protect against bone loss, which is even better. "

More info: Rastelli AL, Taylor, Gao F, Armamento Villareal-R, S-Jamalabadi Majidi, Napoli n., Ellis, MJ. Vitamin d and aromatase inhibitor-induced musculoskeletal symptoms (AIMSS): a phase II, double-blind, placebo-controlled, randomized trial separated. Research on breast cancer and treatment. Online June 2011.

Provided by Washington University School of Medicine (news: web)


View the original article here

Monday, September 5, 2011

New study highlights role of genetics in recovery from eating disorders

A significant number of people with eating disorders like anorexia nervosa have chronic studies. Are underweight and have a great chance of dying from malnutrition. No medication has been found that helps people who are chronically ill. Now, a new study sheds light on why some people have bad results.

An international team of scientists led by researchers at the University of California, San Diego School of Medicine (UCSD), and the Scripps Translational Science Institute (STSI) in La Jolla, CA, has identified possible genetic variations that could affect the patient's recovery from an eating disorder such as anorexia or bulimia. Their findings, reported online in the Journal Neuropsychopharmcology, may provide new insights into developing effective interventions for more treatment-resistant patients with these disorders.

"This study highlights important ' or ' genetic variations SNPs within a person's DNA, associated with long-term, chronic eating disorders," said Walter h. Kaye, MD, Professor of Psychiatry and Director of the UCSD eating disorder treatment and research program, who was a senior writer with Ph.d., Nicholas j. Schork, Director of Bioinformatics and Biostatistics to STSI and Professor at the Scripps Research Institute. "These variations indicate genetic Predictor for patients who may be especially susceptible to eating disorders and diseases are more difficult to treat effectively.

Kaye said such genetic traits are also linked to people with higher and higher concerns over mistakes – characteristics associated with anorexia and bulimia.

Researchers from the Institute for collaborative study was responsible for the collection of data of the study, scientists at UCSD and STSI led the design of the study and analysis of results.

According to lead study author, cinnamon Bloss, PhD, Assistant Professor at the STSI, conclusions could ultimately help pave the way towards a more individualised approach in treating patients with eating disorders. "Anorexia and bulimia which possibly originate from many different causes, such as culture, family, life changes and personality traits," Bloss said. "But we know biology and genetics is important in terms of cause and can play a role in how different users respond to treatment. Understanding the genetics behind these treaties are important because ultimately that could help us customize treatment based on the genetic makeup of individuals, with the aim of more personalized and effective treatments. "

Anorexia and bulimia are serious and complex psychiatric disorders. Anorexia nervosa is characterized by an inability to maintain a normal body weight and a relentless pursuit of lachaniase, bulimia is characterized by recurrent episodes of binge eating. Recent studies, researchers, including Kaye speculate that anorexia and bulimia may share some risk factors, and that patients can be genetically predetermined to have personality traits and moods that make them susceptible to eating disorders.

"People with anorexia in particular are often resistant to treatment and lack of awareness of the medical consequences of their behavior, which can lead to chronic, prolonged illness and even death," said Kaye. "Became a problem for us, ' Prognostic factors Exist that could help clinicians to identify good versus poor results for treatments, including medications and psychotherapies? '"

The research team studied a total of 1,878 women in large-scale candidate gene Association study that was designed based on assumptions regarding the genes, pathways, and biological systems involved in sensitive to eating disorders. Most were people with lifetime diagnosis of either anorexia or anorexia and bulimia, hosted and lower body mass index, higher and higher concerns over mistakes from control issues.

Scientists identified then the top 25 most statistically significant SNPs (single nucleotide-other), after assessing a total of 5,151 SNPs in approximately 350 genes. According to Bloss, 10 of the 25 most strongly associated "haplotypes" (combinations of alleles for different genes are closely together on the same chromosome and who tend to be inherited together) involved in GABA genes, SNPs. An intronic SNP on chromosome 4 gene GABRGI showed the strongest correlation in chronic symptoms. "The study suggests that genes can be pre-dispose people in a cycle of chronic eating disorder," Bloss said, adding that additional studies are needed to confirm these compounds.

Provided by the University of California-San Diego (news: web)


View the original article here

New study highlights role of genetics in recovery from eating disorders

A significant number of people with eating disorders like anorexia nervosa have chronic studies. Are underweight and have a great chance of dying from malnutrition. No medication has been found that helps people who are chronically ill. Now, a new study sheds light on why some people have bad results.

An international team of scientists led by researchers at the University of California, San Diego School of Medicine (UCSD), and the Scripps Translational Science Institute (STSI) in La Jolla, CA, has identified possible genetic variations that could affect the patient's recovery from an eating disorder such as anorexia or bulimia. Their findings, reported online in the Journal Neuropsychopharmcology, may provide new insights into developing effective interventions for more treatment-resistant patients with these disorders.

"This study highlights important ' or ' genetic variations SNPs within a person's DNA, associated with long-term, chronic eating disorders," said Walter h. Kaye, MD, Professor of Psychiatry and Director of the UCSD eating disorder treatment and research program, who was a senior writer with Ph.d., Nicholas j. Schork, Director of Bioinformatics and Biostatistics to STSI and Professor at the Scripps Research Institute. "These variations indicate genetic Predictor for patients who may be especially susceptible to eating disorders and diseases are more difficult to treat effectively.

Kaye said such genetic traits are also linked to people with higher and higher concerns over mistakes – characteristics associated with anorexia and bulimia.

Researchers from the Institute for collaborative study was responsible for the collection of data of the study, scientists at UCSD and STSI led the design of the study and analysis of results.

According to lead study author, cinnamon Bloss, PhD, Assistant Professor at the STSI, conclusions could ultimately help pave the way towards a more individualised approach in treating patients with eating disorders. "Anorexia and bulimia which possibly originate from many different causes, such as culture, family, life changes and personality traits," Bloss said. "But we know biology and genetics is important in terms of cause and can play a role in how different users respond to treatment. Understanding the genetics behind these treaties are important because ultimately that could help us customize treatment based on the genetic makeup of individuals, with the aim of more personalized and effective treatments. "

Anorexia and bulimia are serious and complex psychiatric disorders. Anorexia nervosa is characterized by an inability to maintain a normal body weight and a relentless pursuit of lachaniase, bulimia is characterized by recurrent episodes of binge eating. Recent studies, researchers, including Kaye speculate that anorexia and bulimia may share some risk factors, and that patients can be genetically predetermined to have personality traits and moods that make them susceptible to eating disorders.

"People with anorexia in particular are often resistant to treatment and lack of awareness of the medical consequences of their behavior, which can lead to chronic, prolonged illness and even death," said Kaye. "Became a problem for us, ' Prognostic factors Exist that could help clinicians to identify good versus poor results for treatments, including medications and psychotherapies? '"

The research team studied a total of 1,878 women in large-scale candidate gene Association study that was designed based on assumptions regarding the genes, pathways, and biological systems involved in sensitive to eating disorders. Most were people with lifetime diagnosis of either anorexia or anorexia and bulimia, hosted and lower body mass index, higher and higher concerns over mistakes from control issues.

Scientists identified then the top 25 most statistically significant SNPs (single nucleotide-other), after assessing a total of 5,151 SNPs in approximately 350 genes. According to Bloss, 10 of the 25 most strongly associated "haplotypes" (combinations of alleles for different genes are closely together on the same chromosome and who tend to be inherited together) involved in GABA genes, SNPs. An intronic SNP on chromosome 4 gene GABRGI showed the strongest correlation in chronic symptoms. "The study suggests that genes can be pre-dispose people in a cycle of chronic eating disorder," Bloss said, adding that additional studies are needed to confirm these compounds.

Provided by the University of California-San Diego (news: web)


View the original article here

Thursday, September 1, 2011

One of the six fast-food customers cut calories after U.S. food import emfainoysas system

Approximately one-sixth of the customers used fast food calorie information and, on average, lower calories foods acquired since the introduction of a labelling system in the United States, says a new study published today in the British Medical Journal.

US researchers found there was a small but positive impact from a law introduced in 2008 in New York that require chain restaurants with 20 or more branches at the national level, to provide calorie information on menus and menu boards of the city.

Rates of obesity in the United States at a high in both adults and children and is currently one-third of adults and 17% of children of all ages and adolescents are obese. Several studies support an association between fast food consumption and excessive energy intake, but customers often underestimate the number of calories on restaurant meals and before 2007, nutrition information was rarely available at the time of purchase.

Thus, a team of researchers decided to assess the impact of calorie labelling regulation on the energy content of the individual markets in fast food restaurants in New York. High street chains in England are going to launch a similar scheme, though optional, as part of the Deal the Government responsible for public health.

Investigations completed during lunch hours in spring 2007 (one year prior to the regulation) and in the spring of 2009 (nine months after implementation) randomly selected locations in 168 chains of fast food top 11 in the city.

Adult customers supplied in the registry collection and answers to the questions of the survey. Analyzed data from customers in a customers 2007 7,309 and 8,489 2009.

Overall, there has been no reduction in calories purchased across the full sample. However, the three big chains saw significant reductions.

For example, McDonalds, average energy per market decreased by 5.3% to Au Bon Pain, decreased by 14.4% and KFC, decreased by 6.4%. Together, these three chains represented 42% of all customers of the study.

However, the average energy content increased in the chain – Metro – by 17.8%, which was to a large extent, large parts.

The analysis also showed that 15% of clients reported using the calorie information and, on average, these customers purchased 106 fewer as by customers who do not see or use the information in calories.

Researchers say that calorie labelling is only part of a framework for addressing the epidemic of obesity and solicit additional strategies for reducing energy intake by the population. "We must focus particular attention on about training customers on how to interpret and use nutrition information" award.

In an accompanying editorial, Dr Susan Jebb from MRC human nutrition research center at Cambridge believes that labelling is one step forward, but must follow the changes in the food supply. She writes: "Calorie labeling will help consumers to make an informed choice about what they eat, but steady improvement in the diet of the nation will require a transformation of the food supply."

Provided by the British Medical Journal (news: web)


View the original article here

One of the six fast-food customers cut calories after U.S. food import emfainoysas system

Approximately one-sixth of the customers used fast food calorie information and, on average, lower calories foods acquired since the introduction of a labelling system in the United States, says a new study published today in the British Medical Journal.

US researchers found there was a small but positive impact from a law introduced in 2008 in New York that require chain restaurants with 20 or more branches at the national level, to provide calorie information on menus and menu boards of the city.

Rates of obesity in the United States at a high in both adults and children and is currently one-third of adults and 17% of children of all ages and adolescents are obese. Several studies support an association between fast food consumption and excessive energy intake, but customers often underestimate the number of calories on restaurant meals and before 2007, nutrition information was rarely available at the time of purchase.

Thus, a team of researchers decided to assess the impact of calorie labelling regulation on the energy content of the individual markets in fast food restaurants in New York. High street chains in England are going to launch a similar scheme, though optional, as part of the Deal the Government responsible for public health.

Investigations completed during lunch hours in spring 2007 (one year prior to the regulation) and in the spring of 2009 (nine months after implementation) randomly selected locations in 168 chains of fast food top 11 in the city.

Adult customers supplied in the registry collection and answers to the questions of the survey. Analyzed data from customers in a customers 2007 7,309 and 8,489 2009.

Overall, there has been no reduction in calories purchased across the full sample. However, the three big chains saw significant reductions.

For example, McDonalds, average energy per market decreased by 5.3% to Au Bon Pain, decreased by 14.4% and KFC, decreased by 6.4%. Together, these three chains represented 42% of all customers of the study.

However, the average energy content increased in the chain – Metro – by 17.8%, which was to a large extent, large parts.

The analysis also showed that 15% of clients reported using the calorie information and, on average, these customers purchased 106 fewer as by customers who do not see or use the information in calories.

Researchers say that calorie labelling is only part of a framework for addressing the epidemic of obesity and solicit additional strategies for reducing energy intake by the population. "We must focus particular attention on about training customers on how to interpret and use nutrition information" award.

In an accompanying editorial, Dr Susan Jebb from MRC human nutrition research center at Cambridge believes that labelling is one step forward, but must follow the changes in the food supply. She writes: "Calorie labeling will help consumers to make an informed choice about what they eat, but steady improvement in the diet of the nation will require a transformation of the food supply."

Provided by the British Medical Journal (news: web)


View the original article here

Sunday, August 28, 2011

Imaging new technique records the activity of the brain in patients suffering from chronic low back pain

Research from Brigham and Women's Hospital (BWH) uses a new imaging technique, arterial spin labeling to display areas of the brain that are activated when patients with low back pain are worsening the usual, chronic pain. This research is published in the August issue of the Journal Anesthesiology.

"This study represents a first step towards providing tools to describe objectively a chronic pain is a subjective experience. We found that when a patient is worsening the grief the usual, there are changes in the activity of the brain, "said Ajay Wasan, MD, MSc, lead author of the paper and a researcher at the management centre at BWH pain."These changes occur in the network of brain areas that process pain and mood. "

Researchers compared 16 patients suffering from chronic low back pain (CLBP) in 16 healthy subjects. Participants submitted three Imaging sessions. The first was a qualification and training session. During the second meeting, researchers used clinical maneuvers, such as pelvic inclination or raising straight leg, temporarily aggravate pain in the back. In the third session, the heat was applied to the skin in a matching volume levels of pain during the second session. Patients rated pain levels before and after the sessions and after boost during the sessions.

During the last two sessions, researchers used arterial spin emfainoysas technique, which allows to quantify the blood flow to particular areas of the brain over time. The amount of blood flow is an indicator of Neuron activity in the region of the brain. They found that there was an increase in activity in the brain of patients with CLBP, only when it faced a worsening of the chronic pain and not during the period of operation of heat or pain in healthy participants. Researchers also note that some of the areas of the brain that is activated when participants experienced a worsening of chronic pain has proved to be linked to other types of pain that found in other studies. However, researchers also observed a number of areas, including activation of upper posterior lobule, which are less often associated with pain in the previous investigation.

"While this study begins to reveal some of the basic physiology of the brain, such as processes pain, most studies are needed to help understand how the brain can change during the processing of pain and to examine the mechanisms of brain pain that improves, '' Wasan said. "We are approaching the description, on an objective level, how the body and the brain reacts when a patient reports having more pain. We are hopeful that this could lead to an understanding of the individual patient and neurocircuitry that knowledge may lead to therapies that are tailored to the individual. "

By Brigham and women's Hospital


View the original article here

Imaging new technique records the activity of the brain in patients suffering from chronic low back pain

Research from Brigham and Women's Hospital (BWH) uses a new imaging technique, arterial spin labeling to display areas of the brain that are activated when patients with low back pain are worsening the usual, chronic pain. This research is published in the August issue of the Journal Anesthesiology.

"This study represents a first step towards providing tools to describe objectively a chronic pain is a subjective experience. We found that when a patient is worsening the grief the usual, there are changes in the activity of the brain, "said Ajay Wasan, MD, MSc, lead author of the paper and a researcher at the management centre at BWH pain."These changes occur in the network of brain areas that process pain and mood. "

Researchers compared 16 patients suffering from chronic low back pain (CLBP) in 16 healthy subjects. Participants submitted three Imaging sessions. The first was a qualification and training session. During the second meeting, researchers used clinical maneuvers, such as pelvic inclination or raising straight leg, temporarily aggravate pain in the back. In the third session, the heat was applied to the skin in a matching volume levels of pain during the second session. Patients rated pain levels before and after the sessions and after boost during the sessions.

During the last two sessions, researchers used arterial spin emfainoysas technique, which allows to quantify the blood flow to particular areas of the brain over time. The amount of blood flow is an indicator of Neuron activity in the region of the brain. They found that there was an increase in activity in the brain of patients with CLBP, only when it faced a worsening of the chronic pain and not during the period of operation of heat or pain in healthy participants. Researchers also note that some of the areas of the brain that is activated when participants experienced a worsening of chronic pain has proved to be linked to other types of pain that found in other studies. However, researchers also observed a number of areas, including activation of upper posterior lobule, which are less often associated with pain in the previous investigation.

"While this study begins to reveal some of the basic physiology of the brain, such as processes pain, most studies are needed to help understand how the brain can change during the processing of pain and to examine the mechanisms of brain pain that improves, '' Wasan said. "We are approaching the description, on an objective level, how the body and the brain reacts when a patient reports having more pain. We are hopeful that this could lead to an understanding of the individual patient and neurocircuitry that knowledge may lead to therapies that are tailored to the individual. "

By Brigham and women's Hospital


View the original article here

Saturday, August 27, 2011

Atlantic Beach

Atlantic Beach
Atlantic Beach welcomes new visitors and vacationers back with a hot sun and a wealth of activities. Enjoy the beautiful beaches and major attractions, while enjoying the historic beauty, heritage and amazing the area is known for.
They say there are at least 101 things to do on the coast of crystal, and we say with certainty that it is true. Atlantic Ocean and the Intracoastal Waterway and rivers winding, water-activities include boat tours, cruises, scuba diving, Tours Ecology, fishing piers and fishing, kayaking and boat rentals and more. Atlantic Beach offers one of the best dive destinations in the United States and its natural beauty is unmatched.
The story is also a major attraction at the Crystal Coast. Visitors can enjoy many fun activities along the beach of the Atlantic. For family fun, miniature golf, bumper cars and jetskis fabulous diversions.
Local heritage is also indicated in attractions such as the historic site and museum Core Sound Waterfowl. Skilled craftsmen also gathered along Atlantic Beach. Galleries, arts and entertainment and craft sales abound.
The Crystal Coast is a golfer's paradise with many top flight courses to choose from. With several golf courses in the region, such as Brandywine Bay, Star Hill and Silver Creek Golf Course, you can play from sun up to sundown.
Fall offers the North Carolina Seafood Festival the first week in October on the waterfront of Morehead City and Atlantic Beach King Makerel tournament in September.
Whether in spring, summer or fall, the beautiful Crystal Coast has something to offer everyone. Atlantic Beach offers the serenity of a lazy one week holiday and a weekend. Call our location in Atlantic Beach real estate and blue water vacation to find your "little place in the sun" today.

Tuesday, August 23, 2011

HSE issues two improvement notices to the IAH

The Institute for animal health has confirmed that it has received the HSE two communications earlier in the year.

The first notice in accordance with the IAH came to them when liquid material leaked some waste from the incineration plant in Pirbright Laboratory of the Institute kept. However, the staff was quick to respond to the incident. There were no traces of the virus have been verified in the liquid and all processes and procedures to avoid unwanted incident in the future. The same was the HSE informed.

A joint statement by IAH and biotechnology and biological of Sciences Research Council (BBSRC) said that the second notification because of cracking a container has been issued you virus contained foot and mouth disease. The jump came MBSC safety Cabinet note during the defrost cycle within a class II in a safe organic laboratory. The whole area was cleaned and leaked no germs in the outside world had no risk was involved.

Two notes were sent IAH to that. While the Institute has taken remedial action on one of them, the other that a complaint has been sent, confirmed speakers from HSE. He however comment on the contents of the notes.

The Pirbright site, where the IAH is, became the center of the outbreak of foot and mouth disease in August 2007. no charges have been framed then against it, because the exact cause of the outbreak could not be completed.

HSE issues two improvement notices to the IAH

The Institute for animal health has confirmed that it has received the HSE two communications earlier in the year.

The first notice in accordance with the IAH came to them when liquid material leaked some waste from the incineration plant in Pirbright Laboratory of the Institute kept. However, the staff was quick to respond to the incident. There were no traces of the virus have been verified in the liquid and all processes and procedures to avoid unwanted incident in the future. The same was the HSE informed.

A joint statement by IAH and biotechnology and biological of Sciences Research Council (BBSRC) said that the second notification because of cracking a container has been issued you virus contained foot and mouth disease. The jump came MBSC safety Cabinet note during the defrost cycle within a class II in a safe organic laboratory. The whole area was cleaned and leaked no germs in the outside world had no risk was involved.

Two notes were sent IAH to that. While the Institute has taken remedial action on one of them, the other that a complaint has been sent, confirmed speakers from HSE. He however comment on the contents of the notes.

The Pirbright site, where the IAH is, became the center of the outbreak of foot and mouth disease in August 2007. no charges have been framed then against it, because the exact cause of the outbreak could not be completed.

Saturday, August 20, 2011

7 Year-old girl caught in the swimming pool for more than 2 minutes

Basildon magistrates' Court instead of Castle point Borough Council guilty for violation of section 3 paragraph 1 of the health and safety at work, and so on. Be Canvey Iceland 1974, when a young girl at the age of 7 years met with an accident at the waterside swimming pool in the middle on May 2, 2009. You were fine £ 18,000 and costs of £ 7,500.

The HSE explored the matter said that with her great grandfather owned the Castle point Borough Council pool swim this young girl was gone. Suddenly, steckengeblieben their leave her hair in a vent of the water sampling outlet to the pool for almost 2 minutes and 36 seconds after air snatch. Her great-grandfather had take a cluster of her hair, to get them back to safety. She was on unconscious, blue and limp from the water, but slowly gained awareness brought.

The investigations revealed that the owner of the pool, who were also responsible for the security of its members it had failed to carry out their obligations with respect to the safety of the public with its pool. They had only a vent instead of two in the example outlet and therefore was not a back up for the fall that has blocked a vent. There were only two lifeguards in the service of those who fail at the see see the other the pool note the girl who caught because of the glare of the Sun, was while cleaning. The Court on hearing the HSE, the Council for the accident blamed.

7 Year-old girl caught in the swimming pool for more than 2 minutes

Basildon magistrates' Court instead of Castle point Borough Council guilty for violation of section 3 paragraph 1 of the health and safety at work, and so on. Be Canvey Iceland 1974, when a young girl at the age of 7 years met with an accident at the waterside swimming pool in the middle on May 2, 2009. You were fine £ 18,000 and costs of £ 7,500.

The HSE explored the matter said that with her great grandfather owned the Castle point Borough Council pool swim this young girl was gone. Suddenly, steckengeblieben their leave her hair in a vent of the water sampling outlet to the pool for almost 2 minutes and 36 seconds after air snatch. Her great-grandfather had take a cluster of her hair, to get them back to safety. She was on unconscious, blue and limp from the water, but slowly gained awareness brought.

The investigations revealed that the owner of the pool, who were also responsible for the security of its members it had failed to carry out their obligations with respect to the safety of the public with its pool. They had only a vent instead of two in the example outlet and therefore was not a back up for the fall that has blocked a vent. There were only two lifeguards in the service of those who fail at the see see the other the pool note the girl who caught because of the glare of the Sun, was while cleaning. The Court on hearing the HSE, the Council for the accident blamed.

Tuesday, August 16, 2011

First Borderlands 2 Teaser Trailer


Borderlands 2 is coming to scratch that loot game itch you may have! New characters, weapons, abilities, and more!

Now apparently the previous characters in the first Borderlands will make an appearance but will not be playable. Hence the new character, Salvador, the Gunzerker (I swear he's not based off me!).

To see what we have to look forward to early next year, hit the jump for the teaser trailer that is all "in game" according to Gearbox.

More after the Jump! -->

Hampshire roofing company fined more than £ 34,000 for polluting environment with asbestos

A recent decision against concept Services Ltd provides the fact coverings and sheathing, that asbestos particles are not only very dangerous for the health and safety of the community, but also all companies, the violation of the asbestos be laws severely punished.

The case turned to a serious breach back concept covers and panels Services Ltd, which regard to accomplish the restore asbestos roof of 12 commercial units were asbestos two years in bath street in market Harborough between December 2008 and the end of January 2009. However, the case got at the highlighted and health controls specialists by Leicestershire County Council premises and asbestos found elements in Opera.

But everything, that this was done during the cleaning asbestos roof of concept roofing and cladding Services Ltd. tiled roof company to the water under full pressure when cleaning of asbestos tiles of the necessary legal method asbestos tiles carefully wash with water in a container. The complete Gush water next to the cleaning of asbestos tiles scattered also asbestos into the environment. With objections of traders due to the polluted environment, work ended abruptly when the heavy contamination came also to the attention of the company. Clean-Up of asbestos was then done by a qualified asbestos removal company monitoring the contamination to such a large scale and the presence of asbestos in the air, companies had to shut for many months with empty field close down their services and the car. Cleaning up asbestos took several months, during which the workers understood the extent of the situation, if contaminated their marks on the walls, asbestos was found in drains and bus stops.

Transaction of the whole thing, and the understanding of the seriousness of the case, Leicester magistrates' Court recently pursued and punished the company for violating the regulation 16 of the control of asbestos programme Regulations 2006. Although concept roofing and cladding Services Ltd accepts his mistake it was punished costs £ 12,000 in £ 22,375 as persecution.

According to the report cited in Leicester mercury said of concept covers and panels Stephen Climie Services Ltd, which up to 5 m was a subcontractor company and commissioned, cleaning asbestos roofs in the twelve business firms. However, even, before she had begun their work, almost four business areas already damaged were and drips and polluted area.

Hampshire roofing company fined more than £ 34,000 for polluting environment with asbestos

A recent decision against concept Services Ltd provides the fact coverings and sheathing, that asbestos particles are not only very dangerous for the health and safety of the community, but also all companies, the violation of the asbestos be laws severely punished.

The case turned to a serious breach back concept covers and panels Services Ltd, which regard to accomplish the restore asbestos roof of 12 commercial units were asbestos two years in bath street in market Harborough between December 2008 and the end of January 2009. However, the case got at the highlighted and health controls specialists by Leicestershire County Council premises and asbestos found elements in Opera.

But everything, that this was done during the cleaning asbestos roof of concept roofing and cladding Services Ltd. tiled roof company to the water under full pressure when cleaning of asbestos tiles of the necessary legal method asbestos tiles carefully wash with water in a container. The complete Gush water next to the cleaning of asbestos tiles scattered also asbestos into the environment. With objections of traders due to the polluted environment, work ended abruptly when the heavy contamination came also to the attention of the company. Clean-Up of asbestos was then done by a qualified asbestos removal company monitoring the contamination to such a large scale and the presence of asbestos in the air, companies had to shut for many months with empty field close down their services and the car. Cleaning up asbestos took several months, during which the workers understood the extent of the situation, if contaminated their marks on the walls, asbestos was found in drains and bus stops.

Transaction of the whole thing, and the understanding of the seriousness of the case, Leicester magistrates' Court recently pursued and punished the company for violating the regulation 16 of the control of asbestos programme Regulations 2006. Although concept roofing and cladding Services Ltd accepts his mistake it was punished costs £ 12,000 in £ 22,375 as persecution.

According to the report cited in Leicester mercury said of concept covers and panels Stephen Climie Services Ltd, which up to 5 m was a subcontractor company and commissioned, cleaning asbestos roofs in the twelve business firms. However, even, before she had begun their work, almost four business areas already damaged were and drips and polluted area.

Monday, August 15, 2011

The Fighting Game Renaissance Continues!!! Street Fighter X Tekken Gameplay


This week is Gamescom, the world's largest video game event held in Cologne, Germany. So you can expect some big news and info on the biggest games coming out of it.

So let's kick it off with some Street Fighter X Tekken gameplay! This trailer not only displays some new characters like Ibuki, Kuma, and Yoshimitsu but also highlights some of the gameplay features like Cross Arts.

All the Shoryukens and roundhouse kicks after the jump.


More after the Jump! -->

New Trailer Reveals New Villain For Batman: Arkham City




Ice to meet you!
The villains just keep adding up in Batman: Arkham City. You got The Joker, Penguin, Two Face, The Riddler, and now another joins the fold.

I'm pretty sure that picture gave away which villain this trailer is about. I will give you a hint, it's not the Terminator. He wasn't a Batman villain.

If you haven't figured it out yet, the trailer after the jump should clear it right up for you.

More after the Jump! -->

Friday, August 12, 2011

Counter-Strike: Global Offensive Announced By Valve


It's no Half-Life 2: Episode 3 (or Half-Life 3) but Valve has announced a new game! Called Counter-Strike: Global Offensive, it's definitely something for shooter fans to be excited about, and not just PC shooting fans either.

Hit the jump for all the details.


More after the Jump! -->

Agency for road safety

EU-OSHA (European Agency for safety and health) takes some of the initiatives for the prevention of road accidents, that work regularly faced with professional drivers. EU-OSHA has a Web site, to protect the drivers. The site offers the major reports on road accidents of the United Nations Decade of the action programme for road safety (2011-2020).

In 2009, a large number of truck drivers usually on light tasks due to road accidents their lives lost. Record says more than a thousand drivers been the victims of such accidental deaths this year. The victims were mainly vans and truck driver, motorcycle couriers, drivers, buses and coaches, drivers and other groups.

EU-OSHA will continue to say that the trucks and truck drivers are also expected to other hazards faced on the road, such as violence and robberies, dangers of vibration are common problems. You also glide and often fall from their vehicles and have serious injuries on her body. But EU-OSHA stresses the fact that it is the drivers about the dangers that they encounter on the road every day make quite a complicated task. It is to make even more difficult to comply with the General safety standards on road.

Majority of companies in this sector are small business houses and around 10 employees under each of these companies are busy. Much of the workers are also self-employed have an independent work style. .

The EU-OSHA Web sites provide useful practical examples of unwanted incidents on the road, especially in and around Europe. You have provided materials focusing on certain groups, such as drivers, driver of couriers, and similar categories taxi. The initiatives of the EU-OSHA to the road breakdowns include awareness-raising programmes for drivers, who work every day travel. These programs have significantly improved the health and safety of the driver.

Agency for road safety

EU-OSHA (European Agency for safety and health) takes some of the initiatives for the prevention of road accidents, that work regularly faced with professional drivers. EU-OSHA has a Web site, to protect the drivers. The site offers the major reports on road accidents of the United Nations Decade of the action programme for road safety (2011-2020).

In 2009, a large number of truck drivers usually on light tasks due to road accidents their lives lost. Record says more than a thousand drivers been the victims of such accidental deaths this year. The victims were mainly vans and truck driver, motorcycle couriers, drivers, buses and coaches, drivers and other groups.

EU-OSHA will continue to say that the trucks and truck drivers are also expected to other hazards faced on the road, such as violence and robberies, dangers of vibration are common problems. You also glide and often fall from their vehicles and have serious injuries on her body. But EU-OSHA stresses the fact that it is the drivers about the dangers that they encounter on the road every day make quite a complicated task. It is to make even more difficult to comply with the General safety standards on road.

Majority of companies in this sector are small business houses and around 10 employees under each of these companies are busy. Much of the workers are also self-employed have an independent work style. .

The EU-OSHA Web sites provide useful practical examples of unwanted incidents on the road, especially in and around Europe. You have provided materials focusing on certain groups, such as drivers, driver of couriers, and similar categories taxi. The initiatives of the EU-OSHA to the road breakdowns include awareness-raising programmes for drivers, who work every day travel. These programs have significantly improved the health and safety of the driver.

Wednesday, August 10, 2011

Assassin's Creed: Revelations Beta Announced (Update)


Update: IGN just dropped some more details on the beta. All new info after the jump.


The multiplayer for Assassin's Creed: Brotherhood is one of my favorite multiplayer experiences of recent memory. So seeing as Ubisoft just announced via the official Assassin's Creed Facebook page that the newest entries in the series will be getting a multiplayer beta test two months before the game releases, you can only imagine how giddy I am.


That's the good news, unfortunately some of the details as to how to participate may not be to some gamer's liking.


What little details they have given after the jump.

More after the Jump! -->

The 3DS Revival Continues With A New Color



I was considering going out and getting a 3DS this week once the price drop hits, but a recent announcement from Nintendo has swayed that decision.


Not because of something stupid they did mind you, but because they announced a whole new color that will release alongside Star Fox 64 3D come September 9th and I would rather wait for the new color.


Well, it's a new color for North America at least. Japan has had it for a while now.


If you haven't figured it out which color it is yet, there is a bigger picture after the jump that may clarify it for you as to what it's official color name is.


More after the Jump! -->

Tuesday, August 9, 2011

Dead Island Co-Op Trailer



Hey there zombie fans! Are you tired of killing the undead in wave after wave in Black Ops? Or are you looking for something with a tad bit more gore?

Well good news everybody! Dead Island is less than a month away so soon you and your friends will be able to  annihilate the zombie infestation with whatever tools you happen to find at your disposal.

Haven't heard of Dead Island yet? Well hit the jump for the trailer and see what you have been missing!

Warning: Video is for ages 17+ so click at your own risk!

More after the Jump! -->